Polyions and biogenic polyamine are ubiquitous in many important biochemical functions. We propose here to use neutron reflectivity to investigate their potential to induce and manipulate surfactant adsorption at the air-water interface and to promote surface multilayer formation. This is a new project supported by a Leverhulme Trust Grant, (EM-2013-017), and extends a recently completed EPSRC / Unilever funded programme on surface multilayer formation into realm of biogenic polyamines. It has potential for widespread applications and in a greater understanding their biological role.