The sequence files in this project represent a 16S rRNA gene amplicon survey of cold-water coral microbiomes (Primnoa spp.) completed using Roche 454 pyrosequencing with titanium reagents. The 16S rRNA gene was amplified using primers for the V4-V5 region (fwd: 5' AYTGGGYDTAAAGNG, rev: 5' CCGTCAATTYYTTTRAGTTT). Samples from Baltimore Canyon (in the Atlantic Ocean) were collected in 2012. Samples from Norfolk Canyon (in the Atlantic Ocean) were collected in 2012-2013. Samples from the Gulf of Alaska (Tracy Arm Fjord) were collected in 2011-2012.