The data come from the pollen and biomarker analyses of IODP Site U1385 collected during the expedition 339 Mediterranean Outflow in the south-western Iberian margin. We analysed Marine Isotope Stage (MIS) 18 covering the period between 757 ka and 715 ka and provide the new pollen data, i.e. the percentages of the different ecological groups (Mediterranean forest, Mediterranean or sclerophyllous taxa, pioneer trees and shrubs, heathlands and ubiquists) and the total pollen concentration along with the alkenone-based sea surface temperature (SST) and C37:4-based freshwater flux records. Additionally, we provide the pollen percentages of the Mediterranean forest along with SST records for MIS 19 to 17 (795-670 ka).