Generating high quality reference genomes from field collected specimens by optimizing preservation

Sample preservation challenges efforts to generate high-quality reference genomes or pangenomes for all 2 million+ plant and animal species. Here we compare the impacts of storage methods including solutions, temperature, and time on DNA quality and long-read sequencing quality in 10 fish and 4 plant species. We show 95 percent ethanol protects against sample degradation for fish blood (22 C, less than or equal to 6 weeks) and plant tissue (4 C, less than or equal to 3 weeks). Using Nanopore, we assemble high quality reference genomes from three fish and two plant species (contig N50: 6.5-13.8Mb BUSCO completeness: 94.4-99.2 percent QV: 43.8 for M. esculenta).

Identifier
Source https://data.blue-cloud.org/search-details?step=~01264E3578186F562490CEDA28F665FF410BA3C00FF
Metadata Access https://data.blue-cloud.org/api/collections/64E3578186F562490CEDA28F665FF410BA3C00FF
Provenance
Instrument Illumina NovaSeq 6000; PromethION; ILLUMINA; OXFORD_NANOPORE
Publisher Blue-Cloud Data Discovery & Access service; ELIXIR-ENA
Publication Year 2024
OpenAccess true
Contact blue-cloud-support(at)maris.nl
Representation
Discipline Marine Science
Spatial Coverage (-117.284W, 32.758S, -117.243E, 33.056N)
Temporal Coverage Begin 2022-07-09T00:00:00Z
Temporal Coverage End 2022-12-09T00:00:00Z