The Sea-Bird 63 dissolved oxygen optode sensors used on various oceanographic platforms are known to drift over time. Corrections for drift are necessary for accurate dissolved oxygen measurements on the timescale of months to years. Here, drift on 14 Sea-Bird 63 dissolved oxygen optode sensors deployed on Spray underwater gliders over 5 years is described. The gliders with oxygen sensors were deployed regularly for 100-day missions as part of the California Underwater Glider Network (CUGN). A laboratory two-point calibration was performed on the oxygen sensor before and after glider deployment. Sensor drift during 100-day storage periods and 100-day deployments is comparable. Sensor behavior is modeled with a gain that asymptotes to 1.090 ± 0.005 with an e-folding timescale of 3.70 ± 0.361 years. At zero oxygen concentration, the sensor consistently reads around 3 micromol kg-1; a negative offset term is used in addition to the gain to correct the sensor oxygen. The correction procedure removes the error due to long time drift with an uncertainty of 0.5% or 0.5 micromol kg-1 depending on concentration. Suggested procedures for implementing a two-point calibration procedure in the laboratory are discussed. Calibrations must be considered starting 6 months after initial factory calibration to keep error from sensor time drift under 1%. These data accompany a manuscript in Journal of Atmospheric and Oceanic Technology.