As part of a project concerning the fate of nanoparticles in the body we have been studying the kinetic and competitive (or cooperative) aspects of protein adsorption. HSA is likely to be an important protein in this context. However, HSA binds fatty acids and phospholipids (PL) and these are likely to affect its adsorption. We have already studied the effects of myristic acid on HSA adsorption on silica. Myristic acid does not coadsorb with HSA. It either dissociates before adsorption or, at higher concentrations it may partially remove the HSA. Unlike myristic acid, phosphocholines adsorb on silica and we expect a different pattern of behaviour. Preliminary measurements showed an effect but we now have access to the deuterated HSA, which will greatly enhance the sensitivity of the experiment.