The scripts and data are related to the numerical implementation of a quantitative model for ion flow through neural ion channels and a validation of the underlying single ion channel flow model for gramicidin A channels. The model is based on the Poisson-Nernst-Planck (PNP) equations for ion transport and is described in the related publication in detail.

Gramicidin A: A PNP based model for ion flow through single ion channels is established. We validate our results with experimental data by Busath et al. [1998] (files "NaCl.xlsx" and "KCl.xlsx") for gramicidin A channels with NaCl and KCl solutions of different concentrations.

Quantitative Model: We extend the single channel model by calibrating it with whole-cell patch clamp in-house experimental data (file "DataPatchClampIV.xlsx"). We refer to the related publication for information on the experimental setup.

See comments in the scripts for further information.

MATLAB, 9.11.0.1769968 (R2022b)