Self assembly of thermoresponsive gels

DOI

Thermoresponsive gels are widely used for tissue engineering and drug delivery applications. They consist of a thermoresponsive polymer that self-assembles in a 3D network when increasing the temperature above a critical temperature. We have recently designed and synthesised a series of novel triblock amphiphilic thermoresponsive polymers that hold great promise as biocompatible gels for biomedical applications. Here, we propose to use rheo-SANS to simultaneously investigate the self-assembly and the macroscopic rheological behaviour of such polymers across a range of different temperatures and concentrations. To the best of our knowledge, this is the first rheo-SANS study on methacrylate-based ABC triblock copolymers. Its findings will feed into several projects of the PI's and the co-I's groups, providing essential insights for the design of a new class of thermoresponsive gels.

Identifier
DOI https://doi.org/10.5286/ISIS.E.RB1910285-1
Metadata Access https://icatisis.esc.rl.ac.uk/oaipmh/request?verb=GetRecord&metadataPrefix=oai_datacite&identifier=oai:icatisis.esc.rl.ac.uk:inv/101144215
Provenance
Creator Miss Anna Constantinou; Dr Theoni Georgiou; Professor Molly Stevens; Dr James Doutch; Miss Valeria Nele
Publisher ISIS Neutron and Muon Source
Publication Year 2022
Rights CC-BY Attribution 4.0 International; https://creativecommons.org/licenses/by/4.0/
OpenAccess true
Contact isisdata(at)stfc.ac.uk
Representation
Resource Type Dataset
Discipline Photon- and Neutron Geosciences
Temporal Coverage Begin 2019-03-02T09:00:00Z
Temporal Coverage End 2019-03-04T18:32:07Z