Structural evolution of self-assembled cyclic-peptide hydrogels

DOI

Cyclic peptides which can self-assemble into long nanotubes provide unique properties which can be tailored for a diverse range of biomedical applications. Recently, we have demonstrated these peptides can further self-assemble to form a hydrogel under ambient conditions. Hydrogels are very important systems in the biomedical industry as they provide unique properties allowing a wide-range in applications varying form wound care to a scaffold for cell culture. We have characterized these systems using several different techniques, but require the use of SANS to understand the fundamental processes governing their self-assembly, and testing how they behave under different biological conditions. By using this information we can design bespoke peptides, with highly tuned properties ideal for a broad and diverse range of applications.

Identifier
DOI https://doi.org/10.5286/ISIS.E.92918567
Metadata Access https://icatisis.esc.rl.ac.uk/oaipmh/request?verb=GetRecord&metadataPrefix=oai_datacite&identifier=oai:icatisis.esc.rl.ac.uk:inv/92918567
Provenance
Creator Mr Pratik Gurnani; Ms Julia Rho; Dr Sarah Rogers; Dr Ed Mansfield; Dr Steven Huband; Professor Sebastien Perrier; Dr Raoul Peltier; Dr Carlos Sanchez-Cano; Miss Agnes Kuroki; Mr Sean Heinere Tivini Robert Ellacott
Publisher ISIS Neutron and Muon Source
Publication Year 2021
Rights CC-BY Attribution 4.0 International; https://creativecommons.org/licenses/by/4.0/
OpenAccess true
Contact isisdata(at)stfc.ac.uk
Representation
Resource Type Dataset
Discipline Biology; Biomaterials; Chemistry; Engineering Sciences; Life Sciences; Materials Science; Materials Science and Engineering; Natural Sciences
Temporal Coverage Begin 2018-05-06T08:00:00Z
Temporal Coverage End 2018-05-09T08:15:11Z