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Development of a trough for the bulk oil-water interface experiment
A new experimental approach for commissioning a small Langmuir trough with focusing trumpets. This small new trough is designed to remove the need for solid upper substrate,... -
Folated derivatized nanoemulsions for the treatment of cancer
Nanoemulsions (NE) i.e. nanoparticles containing a fluid lipid or oil dispersed in water and stabilized by a surfactant particles have attracted considerable attention as... -
A SANS study of nano-gels with a temperature tunable bio-interface
Hyaluronic acid (HA) plays a key role in tumour cell bio-adhesion and, as such, this interaction opens up possibilities for targeted tumour pathologies We have created a... -
Spin-echo encoded neutron refraction of air bubbles in a fibrous protein gel
Calcium caseinate is a promising candidate to be developed into a meat analogue. When the dough like protein gel is subjected to mild shear and heat, it turned into a pronounced... -
Structural studies on SRF/MRTF/DNA complex
Serum Response Factor (SRF) is a MADS-family transcription factor which controls growth factor-inducible, cytoskeletal, and muscle-specific genes. SRF interacts with MRTF... -
The dynamical transition in dry proteins?
Water plays a critical role in determining the structure and function of biological system. A hydration level, h~0.2 g water/g protein, is often found to be the minimum... -
Solubilisation of membrane protein REAMP in polymer-stabilised nanodiscs
Poly(Styrene-Maleic Acid) (SMA) is increasingly used in the formation of lipid-nanodiscs for structural membrane studies and biophysics. These polymer-formed nanodiscs are an... -
ChipIR Commercial Access Infineon OX08
High-voltage power semiconductor devices, such as IGBTs, diodes and MOSFETs are susceptible to destructive failure due to terrestrial cosmic radiation (CR), notably the nucleon... -
CYCLODEXTRIN-ENCAPSULATION OF PLATINUM-BASED ANTICANCER DRUGS
The goal of the present proposal is the study of supramolecular nanoencapsulation of platinum-based anticancer agents, by INS spectroscopy. A chemically modified cyclodextrin... -
An atomic scale study of chiral Deuterated and N-15 enriched Lysine with Hydr...
This proposal aims to provide an atomistic understanding of the adsorption of the chiral amino acids L- and D-lysine on vermiculite gel using isotopically labelled reagents. Our... -
In-situ Neutron Diffraction Measurement combined with the First Cyclic Deform...
As additive manufacturing (AM) is moving into the production of more heavily loaded end-use components, particularly within the aerospace sector, improved understanding of the... -
Exploring the interactions between vesicles/viruses and supported lipid bilay...
Many biological processes occur at the interface of cells, at the so called cell membrane, such as internalization of biological nanoparticles, including virions, exosomes and... -
In situ crystalline CTE measurements of nuclear graphite as a function of loa...
Graphite bricks are both the moderator and structural components at the heart of the Advanced Gas-cooled Reactor (AGR) cores. Internal stress arises from the moderation role of... -
Twinning in bcc Ti
This dataset has no description
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Cryopreservation of liver cell spheroids used in artificial liver bio-transpl...
The development of new cryopreservation strategies has major potential in medicine, in particular for storage of biological matter. The detailed characteristics of the cooling... -
How complex is complex: an ALC study of a 10-mer helical peptide chain
There have been ALC studies on the interaction of muons with native proteins, but little systematic work that contributes understanding of how spectroscopic information alters... -
Copy of: Dynamics of amyloid protein fibril elongation using isotope-labelled...
This proposal combines small-angle neutron scattering with novel deuteration strategies to investigate amyloid protein fibrils. Variations in dynamics of elongation and breakage... -
Effect of drug structure on solubilisation in a range of surfactant micelles
The aim of the current project is to probe (at the nanometer length scale) the relationship between the structure of a surfactant molecule, the micelles it forms in solution,... -
Momentum distribution of nickel and niobium in the Ni44Nb56 metallic glass by...
Drawing from our proven track record of Neutron Compton scattering (NCS) work performed on VESUVIO spectrometer at ISIS, we propose to extend our research programme of the... -
Fast Neutron Irradiation of Eumelanin
The implementation of organic interfaces for electrical stimulation of cell-tissue constructs is a central goal in the rapidly expanding fields of bioelectronics and...