-
Understanding the nature of perfume / surfactant interactions at interfaces
This proposal is part of a funded (CASE) project, aimed at understanding the delivery of benefit actives (perfumes) to interfaces and the development of new self-assembled... -
A Total Scattering Investigation of the Intermolecular Interactions in Low Aq...
Low bioavailability is a major problem in drug formulation development; low aqueous solubility of an active pharmaceutical ingredient can stall development of a potentially... -
Hydration of NMA
We propose to study the hydration of N-methylacetamide (NMA) at ambient conditions and at two concentrations, namely 1 NMA : 50 H2O and 1 NMA : 15 H2O, by applying the isotopic... -
Local structure and clustering in acetic acid/pyridine mixtures
The aim of this proposed work is to complete our study of the behaviour of acetic acid/pyridine mixtures as a functionof composition, in order to fully characterise the changes... -
Deep Eutectic Solvents: Metal Ion Dissolution
Deep Eutectic Solvents (DES) are molecular mixtures similar to ionic liquids, having melting points below room temperature. However instead of being composed of a salt, the... -
Understanding Sulphur and Nitrogen-Aromatic interactions from liquid structure
Asphaltenes are a complex and problematic fraction of crude oil that can precipitate, alter wettability and stabilise unwanted oil-in-water emulsions. Asphaltenes have a high... -
Nanostructure of a New Class of Deep Eutectic Solvents Derived from Protic Io...
In earlier SANDALS investigations we have shown that protic ionic liquids (PILs) are nanostructured in the bulk, and how dissolved inorganic salts and small molecule solvents... -
Solvation structure of propane/propene in [C4mim][NTf2] ionic liquid
Supported ionic liquid membranes offer potentially lower-energy alternatives to cryogenic distillation for the separation and isolation of light gas olefins (ethene and propene)... -
When like-charged ions attract: Size and distribution of cationic clusters in...
Contrary to the strong electrostatic repulsion between like charged ions, last year the Ludwig group, used IR and NMR spectroscopy combined with computational methods, to reveal... -
Study of quadrupolar interactions in aromatic liquids: Benzene, hexafluoroben...
The non-covalent interactions between aromatic rings are of fundamental importance in large number biological and chemical processes. Examples include protein tertiary... -
Surface properties of biogenic polyaminesurfactant mixtures
Polyions and biogenic polyamine are ubiquitous in many important biochemical functions. We propose here to use neutron reflectivity to investigate their potential to induce and... -
Hydrogenation of frustrated Lewis pairs in solution
It has been postulated that 'Frustrated Lewis Pairs' react after associating in an encounter complex held by dispersion forces, and that is it is this complex that interacts,... -
The hydration of sucralose
We found in our previous experiments (RB numbers 810202 Determination of sugar hydration shell and water structure in different water-sugar mixtures''(glucose, fructose,... -
The structure of prilocaine in solution - crossing the BBB
This dataset has no description
-
Location of the lipophilic drug testosterone propionate at the oil-water inte...
Solubilisation of poorly-water soluble drug in surfactant micelles is an attractive means of increasing the apparent aqueous solubility of such drugs in order to administer the... -
Structure and orientational dipole correlations of liquid acetonitrile
This dataset has no description
-
Using polymer / surfactant mixtures to optimise / enhance perfume delivery to...
This proposal is part of a funded (CASE) project, aimed at understanding the delivery of benefit actives (perfumes) to interfaces and the development of new self-assembled... -
Pre-aggregation of 3-hydroxybenzoic acid in solution
The pharmaceutical intermediate 3-hydroxybenzoic acid (MHBA) is reported to crystallise in two polymorphs. The stable one is obtained by evaporation from methanol solution,... -
Surface activity of biosurfactant (sophorolipid) / surfactant mixtures
Understanding the fundamental aspects of the surface adsorption and self-assembly of biosurfactant and biosurfactant / conventional surfactant mixtures is a major challenge for... -
Structural comparison of peptidomimetic building blocks
Peptidomimetics are synthetic mimics of peptides, the natural building blocks of proteins, and their development is a growing field of science. An underlying theme in recent...
