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Quantifying the Asymmetry in Cell Membrane Mimetic Supported Lipid Bilayers.
Cell membranes are characterised by complex lipid composition and asymmetric distribution of lipids (lipids facing the outside of the cell are different from the lipids that are... -
Higher resolution inspection of the hydrocarbon pool connected with the metha...
The reaction of methanol to form hydrocarbons over zeolite catalysts is an important option for conversion of natural gas or coal to liquid fuels. We have shown previously via... -
Membrane Composition-Dependent Interaction between Beta-Arrestins and Lipid M...
Beta-arrestins are proteins that regulate GPCR signaling, e.g. by recruiting endocytic components to remove the receptor from the plasma membrane. Our fluorescence microscopy... -
Simultaneous INS and Raman studies of lysozyme
The proposers have obtained a dispersive Raman spectrometer that is fibre optically coupled to a custom centrestick that will allow simultaneous Raman and neutron measurements.... -
Investigation of the interactions of perfluoroalkyl substances with model wor...
Perfluoroalkyl substances (PFASs) are fully fluorinated, stabile, and surface-active compounds. They contain both a hydrophobic fluorinated carbon chain and an ionizable... -
Molecular architecture of monolayers formed by novel sterol-modified phosphol...
A family of sterol-modified glycerophospholipids (SML) have been synthesized in which the sn-1 or sn-2 position is covalently attached to cholesterol and the alternative... -
Organisation of Outer membrane protein F at the air/liquid interface
Crystallisation of membrane proteins as a precursor to high resolution structural studies is a significant research bottleneck. We are investigating alternative methods to... -
Pressure-temperature phase diagram of of the Jahn-Teller transition in LaMnO3
The parent compound LaMnO3 of the hole-doped colossal magnetoresistance materials La1-xAxMnO3 (A = Ca, Sr, Ba etc.) has attracted much interest from condensed matter scientists.... -
The influence of transmembrane potential on the orientation of antimicrobial ...
Natural antimicrobials are of great interest, since they are antibiotics that act on the biological membrane, and it is believed that this makes it far more difficult for... -
Tracking the hydrogen in the magnetocaloric La(Fe,Si)13Hx alloy: is the migra...
La(Fe,Si)13 shows a giant magentocaloric effect, which makes it a highly potential candidate as solid coolant in refrigeration systems. The Curie-temperature can be adjusted to... -
Dynamics of amyloid protein fibril elongation using isotope-labelled SANS
This proposal combines optical spectroscopy with neutron scattering using novel labelling strategies to investigate ?amyloid? protein fibrils. Variations in packing and in the... -
Adsorption of perfluoroalkyl substances to a model soil interface to elucidat...
Perfluoroalkyl substances (PFASs) are stable, surface active and fully fluorinated compounds that have both a hydrophobic fluorinated carbon chain and a hydrophilic ionizable... -
Does ozone initiate damage to the main pulmonary surfactant lipid, DPPC, or c...
Exposure to ozone gas can cause inflammation of the airways and breathing difficulties. The initial reaction of ozone is thought to be predominantly with lipids present in the... -
Mechanism Study of Hydrogen (Deuterium) Dynamics and Multifferoics in Geometr...
This dataset has no description
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Floating Lipid Bilayers Created by Vesicle Fusion
'Floating LSupported Bilayers' (FSB's) have become the 'standard' systems used for studying membrane systems using reflectivity at ISIS and other facilities. They are reliable,... -
Vibrational Energy Transfer in a Physical Molecular Gel
Physicals gels formed by small organic gelators are composed of a rigid network formed by the gelator, in which is trapped a large quantity of solvent. They are very promising... -
High-resolution phonon spectra of silicon nitride phases
Silicon nitride is a mechanically tough and light-weight ceramic material able to withstand high temperatures. It is therefore becoming increasingly attractive for use in... -
Characterisation of Protons in Pyrochlore Electrocatalysts
This proposal is about understanding the atomic-scale structure of complex oxides that contain water or protons and that are used as electrocatalyts for water splitting. Such... -
Structural studies of water under negative pressure
Structural studies of water have been made for a wide range of states but little work has been made for ¿stretched water¿, i.e. under negative pressure. This state may be... -
Determining the Structure of Simple Stratum Corneum Lipid Models for Drug Del...
Using a simple model we wish to mimic the lipid structure of the stratum corneum (the top layer of the skin). The simple model offers several advantages to our research area...