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Non-lamellar lipid-based liquid crystalline structures at interfaces - effect...
To understand better the properties of non-lamellar liquid crystalline nanoparticles, LCNP, as delivery vehicles or surface modifying systems, it is crucial to understand how... -
Tuneable Adsorption of Soft Colloids on Model Biomembrane
Understanding how nanoparticles interact with lipid bilayers will potentially have high impact on the development of new drug delivery systems, and on the investigation of their... -
The role of disulphide bridges in the adsorption of globular proteins at the ...
Following our previous study of adsorption of globular lysozyme and BSA at the oil/water interface by neutron reflection, we continue to explore how unfolding of globular... -
Probing binary mixtures of hard spheres
As part of a larger programme we aim to test densely-packed binary mixtures of monodisperse hard sphere powders to determine local structure, to correlate with ratio of... -
Membrane reconstitution of human dihydroorotate dehydrogenase using lipid-det...
Human dihydroorotate dehydrogenase (DHODH) is an integral membrane protein found in mitochondria involved in the biosynthesis of pyrimidines. DHODH oxidizes dihydroorotate with... -
Assessing the interactions of cyclic peptide-polymer conjugates with a lipid ...
Cyclic peptide-polymer nanotubes can readily self-assembly into long nanotubes, and are being extensively studied for drug delivery applications. As such, understanding how... -
Adsorption versus aggregation; Particles and surface of matching material
The balance between particle-surface and particle-particle interactions is entropically driven. We would like to investigate wherever a multiplayer layer adsorption on a... -
Optimisation of a novel biosensor: the structure of the sensing layer
This dataset has no description
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Effect of saponin-rich plant extracts on skin-mimicking model lipid bilayers
Plant-derived biosurfactants of the group of saponins offer an attractive alternative to synthetic surfactants because of their unique foaming and emulsifying properties... -
Surfactant mixing at hydrophilic solid/aqueous interfaces
By applying the regular solution model (RS) to the determination of composition in a mixed surfactant layer adsorbed at a hydrophilic solid/aqueous interfaceand combining it... -
Adsorption of an Anionic Surfactant on Anionic Surfaces in the Presence of Ca...
In this proposal we request beamtime on the Inter reflectometer to study the unexpected adsorption behaviour of the surfactant bis(2-ethylhexyl) sulfosuccinate caesium salt... -
Cationic surfactants adsorbed to titanium dioxide-effect of pH and added elec...
Titanium dioxide (TiO2) is used in a wide range of applications from medical and dental implants to treatment of contaminated air and water streams. However many of the... -
In situ study of destruction of a denatured surface protein by protease (Savi...
New detergents will increasingly rely on sustainable products and the use of enzymes will become ever more important. However, the process of destruction of stains (often... -
The use of lipid sponge-like nanoparticles as carriers for macromolecules and...
Conventional ways to administer and deliver drugs have reached its limitations. These methods can be still used for small and simple molecules. However, new carriers have to be... -
Amyloid β peptide and α-synuclein association at lipidmodel membranes
We plan to investigate the interaction between amyloid proteins and model biomembranes deposited on solid surfaces. The model membranes will be single zwitterionic and mixed... -
Structure of Colloidal Crystals Near a Solid Surface
The structure of colloidal crystals (dispersions of particles that spontaneously order in a regular array) is known to be influenced by solid boundaries. However there are few... -
Neutron Reflection Studies on Adsorption of Myristoyl-L-Carnitine at the Air/...
The acyl-L-carnitines are a group of novel surfactants. Following our recent home laboratory work to synthesize, purify and characterize them, the aim of this proposal is to... -
How do Surfactants Interact with Complex Monoclonal Antibodies at Oil/Water I...
Heavily bio-engineered monoclonal antibodies (mAbs) are an increasingly important trend in the biopharmaceutical industry. However, these mAbs are often destabilised by the... -
Partial structural study at the oil-water interface
In our previous experiment we determined a value for the interfacial width of bare hexadecane-water interface. The NR-determined width was 6.0 ± 1.0 Å, which compares well with... -
Characterising the corrosion/inhibition mechanisms of iron in different envir...
Offshore structures such as wind turbines and oil rigs generally comprise steel structuresessentially ferritic ironand are extremely prone to corrosion, a problem that causes...
