The use of lipid sponge-like nanoparticles as carriers for macromolecules and their interaction with proteins

DOI

Conventional ways to administer and deliver drugs have reached its limitations. These methods can be still used for small and simple molecules. However, new carriers have to be developed for active compounds that are large, like proteins, or that cannot be dissolved in water. One of the proposed methods is the use of lipid based nanoparticles. Lipids are very abundant in the nature; we eat them, we process or digest them and even our cell membranes are formed by lipids. They have the advantage that can organize themselves in different structures depending on the nature of the lipid and its environment. Therefore, these particles are a potential tool for the encapsulation and control release of macromolecules. In addition, lipid based nanoparticles can also be of benefit in the food industry. For example, they can be used to control the delivery of enzymes employed during food processing.

Identifier
DOI https://doi.org/10.5286/ISIS.E.86391420
Metadata Access https://icatisis.esc.rl.ac.uk/oaipmh/request?verb=GetRecord&metadataPrefix=oai_datacite&identifier=oai:icatisis.esc.rl.ac.uk:inv/86391420
Provenance
Creator Dr Rebecca Welbourn; Dr Maxmilian Skoda; Ms Polina Naidjonoka; Professor Tommy Nylander; Ms Maria Valldeperas Badell; Dr Justas Barauskas
Publisher ISIS Neutron and Muon Source
Publication Year 2020
Rights CC-BY Attribution 4.0 International; https://creativecommons.org/licenses/by/4.0/
OpenAccess true
Contact isisdata(at)stfc.ac.uk
Representation
Resource Type Dataset
Discipline Biology; Biomaterials; Engineering Sciences; Life Sciences; Materials Science; Materials Science and Engineering
Temporal Coverage Begin 2017-05-25T08:00:00Z
Temporal Coverage End 2017-05-27T08:00:00Z