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Interaction of polypeptides with surfactants: SANS study of solution aggregation
This proposal constitutes part of our ongoing study towards understanding the solution aggregation of collagen based polypeptides and their interactions with model surfactants.... -
Partially deuterated gradient poly(2-oxazolines): self-assembly studies
Gradient and block copoly(2-oxazoline)s have been prepared comprising a partially deuterated hydrophilic poly(2-methyl-2-oxazoline) part and a hydrogenated... -
Solution aggregation of short peptide surfactants
Short peptide sequences consisting of hydrophobic and hydrophilic amino acid units are capable of self-assembly to lead to interfacial adsorption and solution nano-aggregation.... -
Interaction of Lignosulphonates with model surfactant systems by Small Angle ...
With the biobased economy growing substantially and pressure to reduce reliance on palm and crude oil derived materials, it is vital that the Home and Personal Care industry... -
Solvation of cellulose-derivate polyelectrolyte in mixed solvents and added s...
Carboxymethylcellulose (NaCMC) is the most widely used cellulose derivative; it forms an anionic, water-soluble, polyelectrolyte with vast applications in the food,... -
Evolution of raft formation over time using contrast variation SANS
Small angle neutron scattering will be used in combination with contrast variation as a non-invasive method to detect the presence and size formation of lipid microdomains or... -
Dispersed lamellar phases in dense CO2
This proposal aims to explore these dispersed lamellar phases with a variety of F7H4 derivatives,to help understand their formation in supercritical CO2 (sc-CO2). The focus is... -
SANS study on the aggregation behavior of aza-crown-water soluble conjugated ...
Water-soluble conjugated polymers (WSCP) are an important class of materials which have received great attention as active materials in optoelectronic devices and in biosensing.... -
Self-assembly of proteins and bio-compatible surfactants
Increased environmental pressures and awareness is promoting a major drive towards an increased use of biosurfactants to produce more biosustainable and biodegradable consumer... -
Structural Study of Functional Nucleosome in Solution
Recently, it is reported that the functional nucleosomes, CENP-A nucleosome, H2A.Bbd nucleosome and hexasome, which include variant histone cores, could have flexible and mobile... -
SANS studies of mixed phospholipid:sterol vesicles and their interaction with...
The increasing incidence of pathogenic fungi resistant to treatment with amphotericin B (AmB) has created a demand for novel anti-fungal agents that can circumvent the... -
Developing a general approach to resolution of accessory proteins bound to cl...
Endocytosis plays a central role in allowing the selective transport of molecules, via membrane-derived vesicles, into cells. Vesicle formation is controlled by a complex... -
Surface Layer Structures of Short Peptide Amphiphiles
Short peptide sequences consisting of hydrophobic and hydrophilic amino acid units are capable of self-assembly, leading to interfacial adsorption and solution nano-aggregation.... -
Thermo-responsive control of the stickiness of end-capped-star-block polymers
Associative polymers have a very important role as rheological modifiers, due to their ability to form interconnected networks of hydrophobic domains. Additionally,... -
Measuring phospholipid flip-flop rates across vesicle bilayers
Asymmetry across biological membranes is vital for a wide range of organelle and cellular functions. Significant differences in lipid composition have been found between the... -
Solution aggregation of lipopeptides: SANS structure determination
Lipopeptide surfactants are highly effective at reducing interfacial tension. However, there is a general lack of understanding of the relationship between their molecular... -
Steroidal drug containing dodecyl sulphate monolayers: effect of counterion
An number of potential drugs, including steroidal drugs are extremely water insoluble, limiting their commercialisation as medicines. Solubilisation of drug in surfactant... -
Probing the structure of antibiotic-gold nanoparticle conjugates
In a one-pot synthesis, we are able to produce spherical gold nanoparticles capped with antibiotics, without the use of other chemicals by using the antibiotic as the reducing... -
Interaction of polypeptides with surfactants: aqueous solution aggregation
This proposal constitutes part of our ongoing study towards understanding how collagen based polypeptides interact with ionic surfactants using SANS. Both SDS and C12TAB will be... -
Structure of siRNA containing delivery vehicles: effect of serum
Complexes prepared from cationic, dichain lipid (L) vesicles and negatively charged siRNA (R), with and without positively chargely targeting peptides (P) known as LR or LPR...