Effect of Temperature on the Transbilayer Structure of a Model Erythrocyre Membrane.


In recent years, it has become understood that rather than being homogenous mixtures, biomembranes show a complex phase behaviour, with regions of uniform phases, and others where the membranes separate into domains. Three component membranes of Sphingomyelin/(D)POPC/Cholesterol have been much studied in recent years as models of eukaryotic membranes. The lateral organisation of these membranes as a function of temperature and composition have been well studied, but little is known about the changes in membrane thickness and rougness between the phases. This information gives insights into changes in lipid packing and membrane fluidity, and so in this experiment we wish to examine the transbilayer structure of the bilayers accross the main thermal 'melting' transition. This will give complementary information to our studies of lateral organisation carried out by BAM.

DOI https://doi.org/10.5286/ISIS.E.24088986
Metadata Access https://icatisis.esc.rl.ac.uk/oaipmh/request?verb=GetRecord&metadataPrefix=oai_datacite&identifier=oai:icatisis.esc.rl.ac.uk:inv/24088986
Creator Dr Stephen Roser; Miss Emma Daulton; Professor Jayne Lawrence; Dr Arwel Hughes
Publisher ISIS Neutron and Muon Source
Publication Year 2015
Rights CC-BY Attribution 4.0 International; https://creativecommons.org/licenses/by/4.0/
OpenAccess true
Contact isisdata(at)stfc.ac.uk
Resource Type Dataset
Discipline Photon- and Neutron Geosciences
Temporal Coverage Begin 2012-05-18T06:54:32Z
Temporal Coverage End 2012-05-20T21:46:58Z