Updated results to publication “Estimation of Recombination Rate and Maternal Linkage Disequilibrium in Half-Sibs” (Fron Genet)

DOI

In Hampel et al. (2018, Fron Genet), we proposed an advanced method for the estimation of paternal recombination rate and maternal linkage disequilibrium between pairs of SNPs if genotypes of paternal half sibs were available. To show practical usability of the approach, empirical bovine data comprising several half-sib families have been investigated. However, the outcome of our method strongly depended on the order of SNPs. For instance, candidates of putatively misplaced SNPs were identified if recombination rate between close SNPs was unusually high. Since the bovine genome assembly has been updated to its current version ARS-UCD1.2, it was necessary to re-analyse the data. The parameter estimates as well as the input data are now jointly available from this repository. More details about the methodology can be found in Hampel et al. (2018, Fron Genet), https://doi.org/10.3389/fgene.2018.00186.

Identifier
DOI https://doi.org/10.22000/280
Related Identifier https://doi.org/10.3389/fgene.2018.00186
Metadata Access https://www.radar-service.eu/oai/OAIHandler?verb=GetRecord&metadataPrefix=datacite&identifier=10.22000/280
Provenance
Creator Wittenburg, Dörte ORCID logo
Publisher Leibniz Institute for Farm Animal Biology (FBN), Wilhelm-Stahl-Allee 2, 18196 Dummerstorf, Germany
Contributor RADAR
Publication Year 2020
Funding Reference Federal Ministry of Education and Research (BMBF) 0315137 Other
Rights Open Access; Creative Commons Attribution 4.0 International; info:eu-repo/semantics/openAccess; https://creativecommons.org/licenses/by/4.0/legalcode
OpenAccess true
Representation
Resource Type genotypic data; Dataset
Format application/x-tar
Discipline Biology; Life Sciences