The quantitative data form in this data-set are derived from a semi-experimental study. The primary objective was: Primary endpoint (1) To assess the effect of the multi-component adherence intervention (MCAI) compared to care as usual on medication persistence (measured by pharmacy records) in persons older than 50 years with a recent fracture that attend the fracture liaison service and have an indication to start anti-osteoporosis medication (with focus on specifically bone resorption inhibitors but also bone formation medication when indicated) . The secondary objectives were: (2) To understand the influence of this MCAI on (i) the relevant aspects of the decision making process (SMD-9) and on decisional conflict (DCS), (ii) on medication initiation and medication possession rate, (iii) on health status (health related quality of life, subsequent fracture and mortality), and (iv) societal costs. (3) To assess experiences of healthcare professionals and patients with the MCAI (process evaluation). (4) To estimate the societal lifetime cost-effectiveness of the MCAI compared to usual care