Low-coverage whole genome sequencing data and DNA barcodes for Pocillopora coral samples collected from sites in Panama, Costa Rica, Colombia, Ecuador, and Clipperton Atoll. This NCBI BioProject contains genomic and DNA barcode records that were generated with financial and technical support from the Federally funded Smithsonian Institution Barcode Network with use of facilities at the Laboratories of Analytical Biology, National Museum of Natural History, Smithsonian Institution.