Membrane interactions of a viral scission protein

DOI

Influenza virus is a pathogen of great medical importance that causes seasonal epidemics and sporadic pandemics. Among the least understood events of the influenza virus lifecycle are the processes that mediate the formation of new viruses and their release from the host cell by membrane scission. Recently we have found a novel role for the influenza virus M2 protein in virus budding, the mediation of membrane scission. The aim of this research is to investigate the molecular details of how M2 alters the shape of the membrane. This will be determined by studying the interactions of the M2 protein with a lipid membrane using neutron reflectivity.

Identifier
DOI https://doi.org/10.5286/ISIS.E.73945207
Metadata Access https://icatisis.esc.rl.ac.uk/oaipmh/request?verb=GetRecord&metadataPrefix=oai_datacite&identifier=oai:icatisis.esc.rl.ac.uk:inv/73945207
Provenance
Creator Ms Agnieszka Martyna; Dr Jeremy Rossman; Dr Basma Bahsoun; Dr Luke Clifton
Publisher ISIS Neutron and Muon Source
Publication Year 2019
Rights CC-BY Attribution 4.0 International; https://creativecommons.org/licenses/by/4.0/
OpenAccess true
Contact isisdata(at)stfc.ac.uk
Representation
Resource Type Dataset
Discipline Biology; Biomaterials; Engineering Sciences; Life Sciences; Materials Science; Materials Science and Engineering; Medicine
Temporal Coverage Begin 2016-02-19T08:00:00Z
Temporal Coverage End 2016-02-21T08:00:00Z