The human body has a well developed membrane chemistry which allows transport of fluids and salts whilst preventing other molecules and harmful agents from penetrating the cell. Transport of drugs and other benefit agents relies on developing agents which behave like the constituents of the cell membrane but then release their payload on entering the cell. The aim of this proposal is to establish how modifying the chemistry of a copolymer which forms tubes at a high pH can be manipulated to give the appropriate degree of pH response in order to ultimately develop a suitable delivery system.