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Adsorption of liquid crystal nanostructured particles to model hydrophilic an...
Cubosomes and hexosomes are particles with internal liquid crystal structures of the bicontinuous cubic or reverse hexagonal nanostructures respectively. The nanostructure... -
The high-pressure structures of carbon dioxide hydrate
The gas hydrates offer potential as hydrogen and carbon dioxide storage materials for use either in transport applications or for carbon sequestration. We have discovered a... -
Formulating polymer solutions to stabilise polymeric foams
Polyurethane foams (PUF) are commonly prepared by mixing Pluronic type copolymers and isocyanate reactive monomers in the presence of additives e.g. catalysts, blowing agents... -
Neutron Training Course SLS 2017
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Structure of siRNA containing delivery vehicles: effect of serum
Complexes prepared from cationic, dichain lipid (L) vesicles and negatively charged siRNA (R), with and without positively chargely targeting peptides (P) known as LR or LPR... -
Interfacial structures and competitive adsorption of amphiphilic polymers wit...
Foam stability, appearance and functionality is governed by the thin liquid films between foam bubbles. These films are stabilised by surface active molecules (surfactants and... -
Dynamics of PDMS-g-PDMS bottlebrush polymers
Bottlebrush polymers, backbone with long side chains, are very interesting regarding their architecture, which is different from well known linear polymers. Not only the... -
Phase diagram of LAS molecule: SANS investigation into surfactant and lipid m...
This proposal would like SANS time to better understand the LAS phase diagram. This has been prompted by recent experiments which show the system is not fully understood under... -
SANS studies of Amphotec (aggregates of amphotericin-cholesteryl sulfate)
The anti-fungal agent amphotericin B (AmB) can be administered to patients in aqueous solution complexed with cholesteryl sulfate (CS), and this formulation helps to minimise... -
Interfacial layer structure of lipopeptides adsorbed at the air/water interface
Lipopeptide surfactants are a group of interesting biosurfactants due to their natural origin and their high effectiveness at reducing interfacial tension. However, there is a... -
Aggregation behaviour in solution of cationic conjugated polymers and oligomers
We extend previous work on aggregates formed by cationic conjugated oligomers in water with surfactants and... -
An In-Situ Study of the Formation of Amyloid Fibrils at Polymer Surfaces Usin...
We propose to study the formation of lateral features during insulin amyloid formation on polymer substrates using off-specular neutron reflectivity. This will be done by... -
Isotopic Characterisation of Pore Surface Chemistry in Monolithic MCM-41 Subs...
Porous materials impregnated with metal nanoparticles are extremely useful in catalysis, an industry that had a global turnover in 2010 of over three trillion dollars.... -
Early stages of amyloid aggregate formation
We will study the kinetics of the early stages of aggregate formation in protein solutions under conditions that are known to result in the formation of amyloid protein fibres... -
Molecular interactions between phospholipid monolayers and dimethylsulphoxide
Neutron reflectivity will be employed to investigate the interaction between dimethylsulphoxide and monomolecular films of phosphatidylcholine. The monolayer will be used as a... -
Quasi-elastic neutron scattering using Neutron Spin echo
We propose a measurement of the effectiveness of using the RF flippers on Offspec in a quasi-elastic mode (theta=90°) with the RF at 0.5MHz. This is important to our future... -
Conformational changes on interaction of cytochrome c with lipid monolayers.
The main objective of the present work is to gain an understanding of the interaction of the cationic protein, cyt c with anionic lipid membranes. This objective will be... -
Di-chain sulfobetaine monolayers at the air-solution interface
Here we wish to continue our investigation of sulfobetaine surfactants in which the charges on the zwitterionic headgroup are reversed compared to those on zwitterionic... -
Probing the Kinetics of Assembly and Triggered Dispersion of Peptide-Function...
Peptide-functionalized nanoparticle (NP) aggregates have significant potential as biosensors (for specific enzymes) due to their high sensitivity, modular design and simple... -
SESANS of beetle scales and butterfly wings
Neutron scattering and in particular SESANS is able to give us excellent ensemble averaging of the optical properties of materials which exhibit structural colour. We plan to...