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Temperature Effects and Kinetics of Thiolipid Adsorption to Gold Surfaces
We have a programme investigating the structure and function of protein scaffolds oriented on gold surfaces using sulfur chemistry for attachment. The aim is to direct the... -
Polymer-Lipid Nanodisc Self-assembly Processes Using Stop Flow
Polymer stabilized lipid nanodiscs offer enormous potential as tools for enabling membrane protein structural studies & biophysics. Polymer stabilized lipid bilayer discs... -
Polymer-Lipid Nanodisc Self-assembly Processes Using Stop Flow
Polymer stabilized lipid nanodiscs offer enormous potential as tools for enabling membrane protein structural studies & biophysics. Polymer stabilized lipid bilayer discs... -
Structural determination of SMA-lipid particles in solution
The development of styrene-maleic acid lipid particles (SMALP) is opening the door to better understanding the nature of membrane proteins, these particles have been well... -
SANS studies of phospholipid:sterol vesicles and the membrane interactions of...
The increasing incidence of pathogenic fungi resistant to treatment with amphotericin B (AmB) has created a demand for novel anti-fungal agents that can circumvent the... -
The influence of transmembrane potential on the orientation of antimicrobial ...
Natural antimicrobials are of great interest, since they are antibiotics that act on the biological membrane, and it is believed that this makes it far more difficult for... -
Structure of oxidised phospholipid bilayers
Biological membranes protect cells and are essential for their survival and damaged membranes may cause serious harm to the cell. A primary cause of damage to membranes is... -
SANS studies of mixed phospholipid:sterol vesicles and their interaction with...
The increasing incidence of pathogenic fungi resistant to treatment with amphotericin B (AmB) has created a demand for novel anti-fungal agents that can circumvent the... -
Assessing the interactions of cyclic peptide-polymer conjugates with a lipid ...
Cyclic peptide-polymer nanotubes can readily self-assembly into long nanotubes, and are being extensively studied for drug delivery applications. As such, understanding how... -
The Orientation and Conformation of an Enantiomeric Pair of 310 Helical Pepti...
We wish to investigate the interactions between peptide mimics of peptaibols, a highly active class of natural antimicrobial peptide, and membranes. In particular we are... -
The Orientation and Conformation of Synthetic 3-10 Helical Peptides within Su...
This dataset has no description
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Self-assembling behaviour of N-acyl amino acid-based surfactants
N-acyl amino acids are surfactants with attractive applications in different technological fields. They are referred to as mild surfactants because they are commonly considered... -
Lipid monolayers at oil/water interfaces at high surface pressure as model bi...
This dataset has no description
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Neutron reflectivity studies of the interaction of amphotericin with phosphol...
The increasing incidence of pathogenic fungi resistant to treatment with amphotericin (AmB) has created a demand for novel anti-fungal agents that can circumvent the pathogens¿... -
Structure of oil-in-water microemulsions containing eutectic mixtures of ment...
Although microemulsions have been widely investigated as potential drug delivery vehicles, relatively little work has been performed establishing the detailed molecular...