Effect of drug on the micelles formed by ionic surfactants
The aim of the study is to use SANS in combination with contrast variation to determine the effect of solubilising the lipophilic drug, testosterone propionate, in micelles formed by the ionic surfactants, sodium dodecyl sulphate and dodecyl trimethylammonium bromide. This study is part of a larger study aimed at understanding the factors influencing the amount of drug solubilised in micelles as well as the influence of drug solubilisation on the size and shape of micellar aggregates.
- 0 6
- 1 2
- 1 2_SANS
- 1 2_TRANS
- 1 6pH_SANS
- 1 6pH_TRANS
- 10
- 10EC
- 10EC 40DDAPS
- 10EC_SANS
- 10EC_TRANS
- 12
- 16EB
- 2 4
- 2 4_TRANS
- 2 _SANS
- 2 _TRANS
- 22EB
- 22EB 40DDAPS
- 22EB_SANS
- 22EB_TRANS
- 24
- 3 _SANS
- 3 _TRANS
- 3B1
- 3C1
- 3C4h
- 3D1
- 3D13L
- 3D2
- 3D5h
- 3D6h
- 3D9M
- 3S1
- 3S2
- 3S3h
- 3S4
- 3S5M
- 3S7L
- 4 8
- 4EB
- 4EB_TRANS
- 4EC
- 52 4 0 1 _SANS
- 52 4 0 1 _TRANS
- 52 4 0 5 _SANS
- 52 4 0 5 _TRANS
- 52 4 1 _SANS
- 52 4 1 _TRANS
- 52 4 2
- 52 5 0 1 _SANS
- 52 5 0 1 _TRANS
- 52 5 0 5 _SANS
- 52 5 0 5 _TRANS
- 52 5 1 _SANS
- 52 5 1 _TRANS
- 52 5 2 _SANS
- 52 5 2 _TRANS
- 68 1 1_SANS
- 68 1 1_TRANS
- 68 2 1_SANS
- 68 2 1_TRANS
- 68 3 0 1 _SANS
- 68 3 0 1 _TRANS
- 68 3 0 5 _SANS
- 68 3 0 5 _TRANS
- 68 3 1_SANS
- 68 3 1_TRANS
- 68 4 1_SANS
- 68 4 1_TRANS
- 69 1 1_SANS
- 69 1 1_TRANS
- 69 2 1_SANS
- 69 2 1_TRANS
- 69 3 1_SANS
- 69 3 1_TRANS
- 70 1 1_SANS
- 70 1 1_TRANS
- 71 1 1_SANS
- 71 1 1_TRANS
- 71 2 1_SANS
- 71 2 1_TRANS
- 71 3 1_SANS
- 71 3 1_TRANS
- 720287
- 73 1 1_SANS
- 73 1 1_TRANS
- 73 2 1_SANS
- 73 2 1_TRANS
- 73 3 1_SANS
- 73 3 1_TRANS
- 73 4 1_SANS
- 73 4 1_TRANS
- 73 5 0 1 _SANS
- 73 5 0 1 _TRANS
- 73 5 0 5 _SANS
- 73 5 0 5 _TRANS
- 73 5 1_SANS
- 73 5 1_TRANS
- 73 6 1_SANS
- 73 6 1_TRANS
- 73 7 1_SANS
- 73 7 1_TRANS
- 73 8 1_SANS
- 73 8 1_TRANS
- 75 1 1_SANS
- 75 1 1_TRANS
- 75 2 1 _SANS
- 75 2 1 _TRANS
- 75 3 1_SANS
- 75 3 1_TRANS
- 76 2 1_SANS
- 76 2 1_TRANS
- 76 4 1_SANS
- 76 4 1_TRANS
- 76 6 1_SANS
- 76 6 1_TRANS
- 77 2 1_SANS
- 77 2 1_TRANS
- 77 4 1_SANS
- 77 4 1_TRANS
- 77 6 1_SANS
- 77 6 1_TRANS
- 78 1 1_SANS
- 78 1 1_TRANS
- 78 2 1_SANS
- 78 2 1_TRANS
- 78 3 1_SANS
- 78 3 1_TRANS
- 78 4 1_SANS
- 78 4 1_TRANS
- 78 5 1_SANS
- 78 5 1_TRANS
- 79 1 1_SANS
- 79 1 1_TRANS
- 79 2 1_SANS
- 79 2 1_TRANS
- 79 3 1_SANS
- 79 3 1_TRANS
- 79 4 1_SANS
- 79 4 1_TRANS
- 79 5 1_SANS
- 79 5 1_TRANS
- 80 1 1_SANS
- 80 1 1_TRANS
- 80 2 1_SANS
- 80 2 1_TRANS
- 80 3 1_SANS
- 80 3 1_TRANS
- 80 4 1_SANS
- 80 4 1_TRANS
- 80 5 1_SANS
- 80 5 1_TRANS
- 81 1 1_SANS
- 81 1 1_TRANS
- 81 3 1_SANS
- 81 3 1_TRANS
- 82 1 1_SANS
- 82 1 1_TRANS
- 82 2 1_SANS
- 82 2 1_TRANS
- 82 3 1_SANS
- 82 3 1_TRANS
- 82 4 1_SANS
- 82 4 1_TRANS
- 82 5 1_SANS
- 82 5 1_TRANS
- 83 1 1_SANS
- 83 1 1_TRANS
- 83 2 1_SANS
- 83 2 1_TRANS
- 83 3 1_SANS
- 83 3 1_TRANS
- 83 4 1_SANS
- 83 4 1_TRANS
- 84 1 1_SANS
- 84 1 1_TRANS
- 84 2 1_SANS
- 84 2 1_TRANS
- 84 3 1_SANS
- 84 3 1_TRANS
- 8EB
- 8EB_SANS
- 8EB_TRANS
- 8EC
- 97_SANS
- 97_TRANS
- B2
- B3_SANS
- B3_TRANS
- Barlow
- Brij
- C10l_SANS
- C10l_TRANS
- C11_SANS
- C11_TRANS
- C12l_SANS
- C12l_TRANS
- C2
- C2h
- C3_SANS
- C3_TRANS
- C6h
- C7m_SANS
- C7m_TRANS
- C8_SANS
- C8_TRANS
- C9m_SANS
- C9m_TRANS
- D10m
- D10m_SANS
- D10m_TRANS
- D11M_SANS
- D11M_TRANS
- D12M_SANS
- D12M_TRANS
- D14L_SANS
- D14L_TRANS
- D14l
- D15L_SANS
- D15L_TRANS
- D20_SANS
- D20_TRANS
- D2O
- D2o
- D3_SANS
- D3_TRANS
- D4
- D6h_SANS
- D6h_TRANS
- D7H_SANS
- D7H_TRANS
- D8h
- DCl_SANS
- DCl_TRANS
- DDAPS_SANS
- DDAPS_TRANS
- DH DTAB
- EB
- EB SDS
- EC
- EC SDS
- H20_SANS
- H20_TRANS
- H2O
- H2O_SANS
- H2O_TRANS
- Jamies
- Jenny s
- Lawrence
- Micelles
- O1C_SANS
- O1C_TRANS
- O1D_SANS
- O1D_TRANS
- O1S_SANS
- O1S_TRANS
- O3C_SANS
- O3C_TRANS
- O3D_SANS
- O3D_TRANS
- O3S_SANS
- O3S_TRANS
- O5C_SANS
- O5C_TRANS
- O5D_SANS
- O5D_TRANS
- O5S_SANS
- O5S_TRANS
- P1C_SANS
- P1C_TRANS
- P1D_SANS
- P1D_TRANS
- P1S_SANS
- P1S_TRANS
- P3C_SANS
- P3C_TRANS
- P3D_SANS
- P3D_TRANS
- P3S_SANS
- P3S_TRANS
- P5C_SANS
- P5C_TRANS
- P5D_SANS
- P5D_TRANS
- P5S_SANS
- P5S_TRANS
- P5Sdil_SANS
- P5Sdil_TRANS
- P7C_SANS
- P7C_TRANS
- P7D_SANS
- P7D_TRANS
- P7S
- P7S_SANS
- P7S_TRANS
- S6m_SANS
- S6m_TRANS
- S8l_SANS
- S8l_TRANS
- SAA
- _SANS
- _TRANS
- aggregates
- aim
- aimed
- amount
- amt
- beam_SANS
- beam_TRANS
- bromide
- buffer_SANS
- buffer_TRANS
- can
- can_SANS
- combination
- conc_SANS
- conc_TRANS
- containing
- contrast
- d SDS
- d2O_SANS
- d2O_TRANS
- dd DTAB
- determine
- dh DTAB
- direct
- dodecyl
- dodecyltrimethlammo...
- drop
- drug
- effect
- empty
- expts_SANS
- expts_TRANS
- factors
- formed
- h DTAB
- h DTAB_SANS
- h DTAB_TRANS
- h SDS
- h SDS_SANS
- h SDS_TRANS
- h20_SANS
- h20_TRANS
- high
- influence
- influencing
- ionic
- larger
- lipophilic
- loq
- low
- max
- micellar
- micelles
- no
- pH
- part
- propionate
- repeat_SANS
- repeat_TRANS
- sans
- shape
- size
- sodium
- sodium dodecyl sulp...
- solubilisation
- solubilised
- solubilising
- standard
- std
- std_SANS
- study
- sulphate
- surfactants
- testosterone
- trimethylammonium
- understanding
- variation
Provenance | |
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Creator | Professor Jayne Lawrence; Dr Dave Barlow |
Publisher | ISIS Neutron and Muon Source |
Publication Year | 2010 |
Rights | CC-BY Attribution 4.0 International; https://creativecommons.org/licenses/by/4.0/ |
OpenAccess | true |
Contact | isisdata(at)stfc.ac.uk |
Representation | |
---|---|
Resource Type | Dataset |
Discipline | Photon- and Neutron Geosciences |
Temporal Coverage Begin | 2007-10-22T07:41:40Z |
Temporal Coverage End | 2007-11-26T23:55:04Z |