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The interaction of oxidatively damaged lung proteins with anionic lipids
Lung surfactant protein B, SP-B, interacts with lipids at the air-water interface of the lung where its presence is vital for correct respiratory function. SP-B and its... -
SANS Investigation into the Mode of Interaction between Antibiotics and Diffe...
In this part of proposed work, we wish to explore how antibiotics minocycline and tetracycline interact with model lipid bilayers in the form of SUVs, mimicking key features of... -
Organisation of Latex Particles in Solution and at the Water/Sapphire Interface
Polystyrene latex represents an excellent model system for studies of the physical properties of colloidal particles. The materials can be prepared with controlled size, and... -
Neutron reflectivity studies of the interaction between novel peptide antibio...
There is an urgent need for development of novel antimicrobial therapies, and the mammalian theta-defensins and protegrins seem to offer significant potential in this regard.... -
Bilayer modification and charge screening by simple ions
Calcium ions have been shown in a preliminary experiment to have a dramatic effect on the thickness and structure of free supported DPPC bilayer films. At low concentrations... -
Order in the bulk and at the surface of dispersions of colloidal particles
Highly ordered dispersions of charged polymer particles that are tens or hundreds of nanometres diameter can be prepared. These are useful model systems for self-assembly and... -
Antimicrobial Mechanisms of Model Biocides via Their Interaction with Lipopol...
The global increase of bacterial resistance to antibiotics has led to increasing interest in research focusing on the development and characterization of new antimicrobial... -
Investigation of the interactions of perfluoroalkyl substances with model wor...
Perfluoroalkyl substances (PFASs) are fully fluorinated, stabile, and surface-active compounds. They contain both a hydrophobic fluorinated carbon chain and an ionizable... -
Colicin interactions with realistic asymmetric models of the bacterial outer ...
The bacterial outer membrane is an important biological surface, where pathogens interact with their victims, the barrier to antibiotics and a source of vaccine components. It... -
The influence of transmembrane potential on the orientation of antimicrobial ...
Natural antimicrobials are of great interest, since they are antibiotics that act on the biological membrane, and it is believed that this makes it far more difficult for... -
Planar bilayer formation on novel cationic surface suitable for membrane prot...
Membrane receptor proteins (MRPs) which are thought to represent the majority of drug targets are challenging to study as their structure and function is dependent on being... -
Does ozone initiate damage to the main pulmonary surfactant lipid, DPPC, or c...
Exposure to ozone gas can cause inflammation of the airways and breathing difficulties. The initial reaction of ozone is thought to be predominantly with lipids present in the... -
Floating Lipid Bilayers Created by Vesicle Fusion
'Floating LSupported Bilayers' (FSB's) have become the 'standard' systems used for studying membrane systems using reflectivity at ISIS and other facilities. They are reliable,... -
The interaction of Plant Defensins with Model Lipid Membranes : Understanding...
Plants do not have the sophisticated immunoglobulin immune systems of vertibrates, instead they posses a series of stimuli based responses which defend against pathogentic... -
pH-control of swelling and charge neutralization of thin hydrogel films
Hydrogels are widely used in biomaterials science, much due to excellent protein resistance, and physicochemical properties similar to biological tissue. Charge neutrality is... -
Membrane-stacking properties of myelin proteins
Myelin is the multilamellar structure that ensheaths axons and accelerates nervous impulses in the nervous system. The fine structure of myelin remains to be further... -
The effect of bilayer rigidity on the interactions with perfluoroalkyl compounds
Perfluoroalkyl substances (PFASs) are used extensively in industrial products although have been identified as emerging pollutants accumulating in wildlife and environment.... -
A complex model of the bacterial outer membrane containing oriented proteins ...
The Outer Membrane (OM) is found in bacteria which cause plague, cholera & Legionnaire¿s disease. It is important as; a barrier to antibiotics & the site of... -
The Interaction of Grp1 with Membranes Containing Signalling Phospholipids
This dataset has no description
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Surfactant Segregation in Plasticised PVA
PVA film is widely used as a non-toxic water soluble polymer. This proposal relates to its use in unit dose detergent pouches where plasticised PVA film stores a concentrated...
